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Multifaceted Compositions for Post-surgical Adhesion Prevention 6,551,610 (2003)
| This invention deals with an absorbable, gel-forming composition for multifaceted prevention of post-operative surgical adhesion through a plurality of physico-pharmacological modes, comprising a solution of one or more bioactive compounds in a liquid copolymeric vehicle made by end-grafting one or more cyclic monomer... read more--> |
Phosphonylated Derivatives of Aliphatic Heterochain and Acrylate Polymers and Applications Thereof 6,551,580 (2003)
| A variety of phosphonylated heterochain polymers are disclosed, including, most preferably, phosphonylated polymethyl methacrylate. For each polymeric composition the phosphorous atom of a phosphorous-containing functional group is covalently bonded to a carbon atom of the polymeric chain. The phosphorous atoms are pre... read more--> |
Copolyesters with Minimized Hydrolytic Instability and Crystalline Absorbable Copolymers Thereof 6,503,991 (2003)
| The present invention is directed to crystalline, absorbable block/segmented copolymers which are the reaction product of a linear prepolymer which is a polytrimethylene dicarboxylate of succinic, glutaric, or adipic acid and either glycolide, 1-lactide, or mixtures thereof. Preferably the prepolymer is preliminarily e... read more--> |
Cyanoacrylate-capped heterochain polymers and tissue adhesives and sealants therefrom 6,699,940 (2004)
| The present invention is directed toward cyanoacrylate-based tissue adhesive or sealant compositions comprising cyanoacrylate-capped heterochain polymers, such as those comprising one or more oxyalkylene, alkylene carbonate, and ester-units derived from cyclic lactones. Such compositions can be radiochemically steriliz... read more--> |
Absorbable Nitrogenous e-caprolactone (.EPSILON.-caprolactone) copolymers and Applications Thereof 6,703,035 (2004)
| This invention deals with crystalline, nitrogen copolyester lubricant coating devices comprising sutures, wherein said lubricant comprises a triaxial copolyester chain with a central nitrogenous base or a copolyester with more than one carboxylic group ionically linked to a basic amino acid.... read more--> |
Polyester/cyanoacrylate tissue adhesive formulations 6,723,114 (2004)
| The present invention is directed to bioabsorbable adhesive/hemostatic formulations of a 2-alkoxyalkylcyanoacrylate and liquid or solid polymeric modifiers and adjuvant. The present adhesive formulations are useful as tissue adhesive/sealants, hemostatic agents, and as a means for patching or anastomic coupling of dama... read more--> |
Antimicrobial Fabrics 6,780,799 (2004)
| The present invention is directed to surface functionalized fabrics, particularly those based on non-woven polypropylene, wherein the functional groups are capable of binding antimicrobial agents through ionic conjugation to control their release and prolong their antimicrobial activity. The invention also deals with N... read more--> |
Amorphous polymeric polyaxial initiators and compliant crystalline copolymers therefrom 6,794,485 (2004)
| An absorbable crystalline, monocentric polyaxial copolymer comprising a central carbon or nitrogen atom and at least three axes, each of which includes an amorphous flexible component adjacent and originating from the central atom and a rigid, crystallizable component extending outwardly from the amorphous, flexible co... read more--> |
Copolyesters with minimized hydrolytic instability and crystalline absorbable copolymers thereof European Patent EP 0 999 227 (2004)
| The present invention is directed to the design of segmented/block copolymeric chains to provide absorbable
materials as for the production of biomedical articles with controlled absorption and strength retention profiles. The
copolymers of the present invention have an amorphous or low melting temperature phase that is based primarily on
soft segments or blocks whose chains are essentially devoid of distinctly hydrolytically labile ester linkages and hence,
provide an overall minimized hydrolytic instability. read more--> |
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