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Interlinked solid polyethylene glycols and copolymers thereof 6,861,503 (2005)
| The present invention is directed primarily to an interlinked crystalline solid polyethylene glycol composition (I-PEG) having a molecular weight of at least 20 kDa and a melting temperature of at least 40.degree. C. and its use as an absorbable device having hydrolabile ester or carbonate interlinks that allow in vivo... read more--> |
Functionalized Absorbable Segmented Copolyesters and Related Copolymers 7,138,464 (2006)
| Absorbable heterochain polymers carrying acid or basic groups, capable of ionic conjugation with basic or acidic bioactive agents, respectively, are produced by free-radical addition of unsaturated functional monomers onto absorbable liquid polymers and subsequent generation of reactive functionality or direct copolyme... read more--> |
Amorphous Polymeric Polyaxial Initiators and Compliant Crystalline Copolymers Therefrom 7,129,319 (2006)
| An absorbable crystalline, monocentric polyaxial copolymer comprising a central carbon or nitrogen atom and at least three axes, each of which includes an amorphous flexible component adjacent and originating from the central atom and a rigid crystallizable component extending outwardly from the amorphous, flexible com... read more--> |
Stabilized Polyester/Cyanoacrylate Tissue Adhesive Formulation 7,083,634 (2006)
| The present invention is directed to adhesive/hemostatic formulations of 2-alkoxyalkyl cyanoacrylate, an absorbable liquid or solid polymeric modifier, and a general stabilizer against premature anionic polymerization of cyanoacrylates. The present formulations are useful as tissue adhesives/sealants... read more--> |
Endosteal Dental Implant D503,803 (2005)
| The ornamental design for an endosteal dental implant, as shown and described.... read more--> |
Coated, slow-absorbing textile constructs for sutures and tissue engineering 7,048,753 (2006)
| The present invention is directed to crystalline copolymers of l-lactide and a minor portion of a cyclic monomer, preferably .epsilon.-caprolactone or trimethylene carbonate or both. The present copolymers have a melting temperature of at least 150.degree. C. and a crystallinity of at least 20%. Preferred are high mole... read more--> |
Vascular Graft European Patent EP 1 582 547 (2005)
| A vascular graft comprising a sealant made of an absorbable crystalline monocentric polyaxial copolyester comprising a central nitrogen atom with chains extending outwardly therefrom. Each chain consists of an inner amorphous component and an outer crystalline component. Each of the components is derived from at least one cyclic monomer selected from the group consisting of glycolide, l-lactide, Ɛ-caprolactone, and trimethylene carbonate read more--> |
Drug-Polymer Coated Stents with Segmented Homochain Copolyesters 7,041,308 (2006)
| The present invention provides a system for treating a vascular condition, including a catheter, a stent coupled to the catheter, a polymeric coating on the stent including a segmented homochain copolyester, and a bioactive drug dispersed within the polymeric coating... read more--> |
Amorphous Polymeric Polyaxial Initiators and Compliant Crystalline Copolymers Therefrom 7,026,437 (2006)
| An absorbable crystalline, monocentric polyaxial copolymer comprising a central carbon or nitrogen atom and at least three axes, each of which includes an amorphous flexible component adjacent and originating from the central atom and a rigid, crystallizable component extending outwardly from the amorphous, flexible co... read more--> |
Hydrogel-forming, self-solvating absorbable polyester copolymers and methods for use thereof European Patent EP 952 171 (2006)
| This invention relates generally to biomedical and/or pharmaceutical applications of absorbable or biodegradable polymeric hydrogels and biologically active agent containing compostions. More particularly, the present invention relates to such compositions wherein the hydrogel-forming, self-solvating, absorbable polyester copolymers are capable of selective, segmental association into compliant hydrogels upon contacting an aqueous environment. They provide controlled release of a biologically active agent for modulating cellular events such as wound healing and tissue regeneration or therapeutic treatment of diseases such as cancer and infection of the periodontium, eye, dry socket, bone, skin, vaginal, and nail infections. read more--> |
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