|
Analytical Testing
Biological Testing/Analysis
Device Prototypes Using
Mechanical Testing
Processing Capabilities
Poly-Med Current and Future Products
Adjunct to PMI's major focus on new technologies and subsequent partnerships with pertinent manufacturing/marketing
companies, we continue to provide technical services to industrial partners and key clients in the biomedical and
pharmaceuticals areas. This is expertly accomplished under the auspices of our Analytical & Validation Center
established as a new division in 1996 and dedicated, in part, to contract GLP and non-GLP activities.
These services are extended to the production of high-value biomaterials for industrial partners since the
Bioengineering Center facilities became operational. PMI currently offers the following services:
Analytical Testing
Chromatography: GPC, HPLC
Spectroscopy: FTIR, NMR, UV-visible, ESCA
Microscopy: Optical, SEM
Melt Rheology
Solution Viscometry
Thermal: DSC, DMA
Particle Size Analysis
Refractometry
Inherent Viscosity (in Chloroform and HFIP)
Conductivity
Optical Microscopy
Thermal Microscopy
Moisture Content
Tin Content
Moisture Analysis
Integrated techniques for product and process trouble-shooting
back to top
Biological Testing/Analysis
Sterility Testing
Cytotoxicity Testing (Agar Diffusion or Elution)
Antimicrobial Susceptibility Testing
Bioburden Test
In vivo Tissue Response
Implant In vivo Absorption
Flow Cytometry
back to top
Device Prototypes Using
Bridgeport Vertical Mill
Jet Lathe
Upright Drill Press
Carver Manual and Hydraulic-Programmable Presses
Heated and Water Cooled Platens
30 Ton Shop Press
CAD Design
Electronic Circuitry Design and PCB Fabrication
Variety of common tooling
3-D Micromachining Units
back to top
Mechanical Testing
Fiber Tensile Testing
In vitro and In vivo Strength Retention
In vivo studies conducted at an AAALAC accredited facility
3-Point Bend Testing
Push-out/Pull-out Testing
Burst Strength Testing
Fabric Peel Testing
Hardness Comparison Testing
Compression Testing
Penetration Testing
back to top
Processing Capabilities
Polymer Grinding and Pelletizing
Micronization
Ethylene Oxide Sterilization
Radiochemical Sterilization
Solid State Orientation
Compression Molding
Injection Molding (Thermoplastics and Silicones)
Fiber Extrusion: Mono- and Multifilament
Tube and Catheter Extrusion
Fiber Drawing and Orientation
BraidingKnitting (Warp, Circular, and Flat)
Surface Activation
Monomer Extraction
Reactive Blending / Extrusion
back to top
Current & Future Products
Polymers and Polymeric Components for Commercial Products
• Osteoprene®: Long-lasting Braided Multifilament Suture
• Glycoprene II®: Absorbable Microfilament
• V-270: Absorbable Cyanoacrylate Tissue Adhesive
for veterinary application
• RD-7: Absorbable Polyaxial Polymer
• Lactoprene II®: Absorbable Braided Multifilament as Components of a Mechanical Femoral Artery Seal
• Liquid Gel-forming
Polymers: Absorbable Polyether-esters
• Polyanionic Absorbable Polyester for Controlled Drug
Microparticles: Release Formulation for Treating Periodontitis
Licensed Technology
• Non-absorbable Stent Coating
Polymers and Polymeric Components for Targeted Commercial Products
• Liquid Gel-forming Polymers and Knitted Multifilament Yarn
• Non-hormonal Intravaginal Contraceptive Ring System
• Antibacterial Intravaginal Ring
• Intravaginal Ring for Treating Yeast Infection
• A Product Line of Absorbable, Non-absorbable, and Silk Sutures with Competitive and/or Unique Properties
• Absorbable/Disintegratable Ureteral Stent (Uriprene®) Composite Radiopaque Ureteral Stent
• Micromantled Drug-Eluting Endovascular Stent, Electrospun Cover (mantle) on Metallic Stent Releasing Bioactive Agent to Prevent Restenosis
• Theraprene-3: Three-drug, bilayer, controlled release, coated tablet containing the analgesic acetaminophen for combination therapy with anti-inflammatory drug and agent for reducing gastric acid secretion
• Theraprene-2: Two-drug, controlled release, tablet of aspirin and an agent for reducing gastric acid secretion
back to top
|
