Patents
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Absorbable and e-caprolactone (.EPSILON.-caprolactone) Polymers and Medical Devices 6,485,749 (2002)
Crystalline, low melting .epsilon.-Caprolactone polymers which undergo accelerated hydrolysis, and their use as lubricant coatings and/or as coatings containing bioactive agents, as carriers of viable cells, and as coatings for open-cell micoporous template or constucts for tissue regeneration; the polymers bearing bas...
Read MoreAbsorbable e-caprolactone (.EPSILON.-caprolactone) Polymers And Medical Devices 6,197,320 (2001)
Crystalline, low melting -Caprolactone polymers which undergo accelerated hydrolysis, and their use as lubricant coatings and/or as coatings containing bioactive agents, as carriers of viable cells, and as coatings for open-cell microporous template or constucts for tissue regeneration; the polymers bearing basic funct...
Read MoreAbsorbable e-caprolactone (.EPSILON.-caprolactone) Polymers as Suture Coating Displaying Autocatalyzed Hydrolysis--Composition 5,773,563 (1998)
Crystane, low melting .epsilon.-Caprolactone polymers which undergo accelerated hydrolysis, and their use as lubricant coatings and/or as coatings containing bioactive agents, as carriers of viable cells, and as coatings for open-cell microporous template or constucts for tissue regeneration; the polymers bearing basic...
Read MoreAbsorbable Nitrogenous e-caprolactone (.EPSILON.-caprolactone) copolymers and Applications Thereof 6,703,035 (2004)
This invention deals with crystalline, nitrogen copolyester lubricant coating devices comprising sutures, wherein said lubricant comprises a triaxial copolyester chain with a central nitrogenous base or a copolyester with more than one carboxylic group ionically linked to a basic amino acid....
Read MoreAbsorbable tissue adhesives 5,350,798 (1994)
Tissue adhesive compositions are disclosed which comprise at least one 2-Cyanoacrylate ester of the general formula (I) [chemical formula is cited in patent] in admixture with from about 2 percent to about 25 percent of at least one oxalic acid polymer of the general formula...
Read MoreAcylated Cyclodextrin Derivatives 5,916,883 (1999)
A cyclodextrin derivative, wherein at least 60 percent of the free hydroxy groups of said cyclodextrin are acylated with acyl groups where at least one of said acyl groups comprise a free carboxylic group....
Read MoreAcylated Cyclodextrin Derivatives 6,204,256 (2001)
A cyclodextrin derivative, wherein at least 60 percent of the free hydroxy groups of said cyclodextrin are acylated with acyl groups where at least one of said acyl groups comprise a free carboxylic group....
Read MoreAmorphous Polymeric Polyaxial Initiators and Compliant Crystalline Copolymers Therefrom 6,462,169 (2002)
An absorbable crystalline, monocentric polyaxial copolymer comprising a central carbon or nitrogen atom and at least three axes, each of which includes an amorphous flexible component adjacent and originating from the central atom and a rigid, crystallizable component extending outwardly from the amorphous, flexible co...
Read MoreAmorphous polymeric polyaxial initiators and compliant crystalline copolymers therefrom 6,794,485 (2004)
An absorbable crystalline, monocentric polyaxial copolymer comprising a central carbon or nitrogen atom and at least three axes, each of which includes an amorphous flexible component adjacent and originating from the central atom and a rigid, crystallizable component extending outwardly from the amorphous, flexible co...
Read MoreAmorphous Polymeric Polyaxial Initiators and Compliant Crystalline Copolymers Therefrom 7,026,437 (2006)
An absorbable crystalline, monocentric polyaxial copolymer comprising a central carbon or nitrogen atom and at least three axes, each of which includes an amorphous flexible component adjacent and originating from the central atom and a rigid, crystallizable component extending outwardly from the amorphous, flexible co...
Read MoreAmorphous Polymeric Polyaxial Initiators and Compliant Crystalline Copolymers Therefrom 7,129,319 (2006)
An absorbable crystalline, monocentric polyaxial copolymer comprising a central carbon or nitrogen atom and at least three axes, each of which includes an amorphous flexible component adjacent and originating from the central atom and a rigid crystallizable component extending outwardly from the amorphous, flexible com...
Read MoreAmorphous polymeric polyaxial initiators and compliant crystalline copolymers therefrom 7,070,858 (2006)
An absorbable crystalline, monocentric polyaxial copolymer comprising a central carbon or nitrogen atom and at least three axes, each of which includes an amorphous flexible component adjacent and originating from the central atom and a rigid, crystallizable component extending outwardly...
Read MoreAntimicrobial Fabrics 6,780,799 (2004)
The present invention is directed to surface functionalized fabrics, particularly those based on non-woven polypropylene, wherein the functional groups are capable of binding antimicrobial agents through ionic conjugation to control their release and prolong their antimicrobial activity. The invention also deals with N...
Read MoreAntimicrobial fabrics 6,596,657 (2003)
The present invention is directed to surface functionalized fabrics, particularly those based on non-woven polypropylene, wherein the functional groups are capable of binding antimicrobial agents through ionic conjugation to control their release and prolong their antimicrobial activity...
Read MoreCoated, slow-absorbing textile constructs for sutures and tissue engineering 7,048,753 (2006)
The present invention is directed to crystalline copolymers of l-lactide and a minor portion of a cyclic monomer, preferably .epsilon.-caprolactone or trimethylene carbonate or both. The present copolymers have a melting temperature of at least 150.degree. C. and a crystallinity of at least 20%. Preferred are high mole...
Read MoreComposite Vascular Constructs with Selectively Controlled Properties 7,371,256 (2008)
This invention deals with a composite vascular construct, which is formed of a first, blood contacting component and a second, tissue contacting component. Preferably, the present vascular constructs are in the form of a...
Read MoreComposition for Prevention of Inflammation and Adhesion Formation and Uses Thereof 5,866,554 (1999)
Pharmaceutical compositions comprising hyaluronic acid, non-steroidal inflammatory drugs, and organic salts of divalent metals, and methods of using these compositions for the inhibition of inflammation and adhesion formation are described....
Read MoreComposition for Prevention of Inflammation and Adhesion Formation and Uses Thereof 6,037,331 (2000)
Pharmaceutical compositions comprising hyaluronic acid, non-steroidal inflammatory drugs, and at least one organic salt of at least one divalent metal, and methods of using these compositions for the inhibition of inflammation and adhesion formation are described. Preferred organic salts of divalent metals include magn...
Read MoreConformable, Absorbable, Solid Composite Preforms and Their Use for Bone Tissue Engineering 7,244,445 (2007)
The present invention is directed to an absorbable, conformable composite perform for use in making a solid bone filler which is an absorbable mixture of oppositely charged, solid microparticulate polyelectrolytes encased in a sealed, flexible, absorbable copolyester fabric construct and is capable of undergoing solidi...
Read MoreConjugated Drug-Polymer Coated Stent 7,264,822 (2007)
One aspect of the invention is a system for treating vascular conditions, including a catheter, a stent coupled to the catheter, and a polymeric coating on the stent comprising at least one conjugated drug. Each conjugated drug includes a control agent and a bioactive agent...
Read MoreContinuous Open Cell Polymeric Foam Containing Living Cells 5,677,355 (1997)
A polymeric foam with continuous, open-cell pores containing living cells suitable for medical applications and methods for preparing these foams. The microporous foams are of controlled pore size that may be utilized in a variety of applications. In general, the foams are characterized in that the pores are continuous...
Read MoreCopolyesters with Minimized Hydrolytic Instability and Crystalline Absorbable Copolymers Thereof 6,255,408 (2001)
The present invention is directed to crystalline, absorbable block/segmented copolymers which are the reaction product of a linear prepolymer which is a polyalkylene dicarboxylate of succinic, glutaric, sebacic or adipic acid and either glycolide, 1-lactide, or mixtures thereof. Preferably the prepolymer is preliminari...
Read MoreCopolyesters with Minimized Hydrolytic Instability and Crystalline Absorbable Copolymers Thereof 6,503,991 (2003)
The present invention is directed to crystalline, absorbable block/segmented copolymers which are the reaction product of a linear prepolymer which is a polytrimethylene dicarboxylate of succinic, glutaric, or adipic acid and either glycolide, 1-lactide, or mixtures thereof. Preferably the prepolymer is preliminarily...
Read MoreCopolyesters with minimized hydrolytic instability and crystalline absorbable copolymers thereof European Patent EP 0 999 227 (2004)
The present invention is directed to crystalline, absorbable block/segmented copolymers which are the reaction product of a linear prepolymer which is a polyalkylene dicarboxylate of succinic, glutaric, sebacic or adipic acid and either glycolide, l-lactide, or mixtures thereof. Preferably the prepolymer is preliminarily end-grafted with one or more monomers such as...
Read MoreCopolyesters with minimized hydrolytic instability and crystalline absorbable copolymers thereof 6,503,991 (2003)
The present invention is directed to crystalline, absorbable block/segmented copolymers which are the reaction product of a linear prepolymer which is a polytrimethylene dicarboxylate of succinic, glutaric, or adipic acid and either glycolide, 1-lactide, or mixtures thereof. Preferably the prepolymer is preliminarily end-grafted...
Read MoreCrystalline High-compliance Glycolide Copolymers and Applications Thereof 7,435,789 (2008)
The present invention is directed toward an absorbable crystalline segmented copolymer comprising a polyalkylene succinate segment end-grafted in a single-step with a mixture of monomers comprising caprolactone...
Read MoreCyanoacrylate-capped heterochain polymers and tissue adhesives and sealants therefrom 6,699,940 (2004)
The present invention is directed toward cyanoacrylate-based tissue adhesive or sealant compositions comprising cyanoacrylate-capped heterochain polymers, such as those comprising one or more oxyalkylene, alkylene carbonate, and ester-units derived from cyclic lactones. Such compositions can be radiochemically steriliz...
Read MoreDirect Synthesis of Segmented Glycolide Copolymers and Crystalline Materials Therefrom 6,498,229 (2002)
The present invention is directed to a method for the direct, one-step synthesis of crystalline segmented glycolide copolymers having less than 80 percent glycolide-based sequences in the copolyester chain. The copolyester chain can also be formed using a polyether glycol as the initiator for the ring-opening copolymer..
Read MoreDrug-Polymer Coated Stents with Segmented Homochain Copolyesters 7,041,308 (2006)
The present invention provides a system for treating a vascular condition, including a catheter, a stent coupled to the catheter, a polymeric coating on the stent including a segmented homochain copolyester, and a bioactive drug dispersed within the polymeric coating...
Read MoreEndosteal Dental Implant D503,803 (2005)
The ornamental design for an endosteal dental implant, as shown and described....
Read MoreFunctionalized Absorbable Segmented Copolyesters and Related Copolymers 7,138,464 (2006)
Absorbable heterochain polymers carrying acid or basic groups, capable of ionic conjugation with basic or acidic bioactive agents, respectively, are produced by free-radical addition of unsaturated functional monomers onto absorbable liquid polymers and subsequent generation of reactive functionality or direct copolyme...
Read MoreHigh strength fibers of L-lactide copolymers .epsilon.-caprolactone and trimethylene carbonate and absorbable medical constructs thereof 6,342,065 (2002)
The present invention is directed to crystalline copolymers of l-lactide and a minor portion of a cyclic monomer, preferably .epsilon.-caprolactone or trimethylene carbonate or both. The present copolymers have a melting temperature of at least 150.degree. C. and a crystallinity of at least 25%...
Read MoreHigh strength fibers of L-lactide copolymers .epsilon.-caprolactone and trimethylene carbonate and absorbable medical constructs thereof 6,342,065 (2002)
The present invention is directed to crystalline copolymers of l-lactide and a minor portion of a cyclic monomer, preferably .epsilon.-caprolactone or trimethylene carbonate or both. The present copolymers have a melting temperature of at least 150.degree. C. and a crystallinity of at least 25%. Preferred are high mole...
Read MoreHigh Strength Fibers of l-Lactide Copolymers, Ɛ-Caprolactone, and Trimethylene Carbonate and Absorbable Medical Constructs Thereof 7,192,437 (2007)
The present invention is directed to crystalline copolymers of l-lactide and a minor portion of a cyclic monomer, preferably Ɛ-carprolactone or trimethylene carbonate or both. The present copolymers have a melting temperature of at least 150ºC and a crystallinity of at least 20%. Preferred are high molecular weight c...
Read MoreHigh Strength Fibers of l-Lactide Copolymers, ε-Caprolactone, and Trimethylene Carbonate and Absorbable Medical Constructs Thereof EP 1260533
The present invention is directed to crystalline copolymers of l-lactide and a minor portion of a cyclic monomer, preferably .epsilon.-caprolactone or trimethylene carbonate or both. The present copolymers have a melting temperature of at least 150.degree. C. and a crystallinity of at least 25%. Preferred are high mole...
Read MoreHydrogel-forming, self-solvating absorbable polyester copolymers and methods for use thereof European Patent EP 952 171 (2006)
This invention relates generally to biomedical and/or pharmaceutical applications of absorbable or biodegradable polymeric hydrogels and biologically active agent containing compostions. More particularly, the present invention relates to such compositions wherein the hydrogel-forming, self-solvating, absorbable polyester copolymers are capable of selective, segmental association into compliant hydrogels upon contacting an aqueous environment. They provide controlled release of a biologically active agent for modulating cellular events such as wound healing and tissue regeneration or therapeutic treatment of diseases such as cancer and infection of the periodontium, eye, dry socket, bone, skin, vaginal, and nail infections...
Read MoreHydrogel-forming, self-solvating absorbable polyester copolymers, and methods for use thereof 5,612,052 (1997)
The present invention provides novel hydrogel-forming, self-solvating, absorbable polyester copolymers capable of selective, segmental association into compliant hydrogels upon contacting an aqueous environment. Methods of using the novel polyester copolymers of the invention in humans are also disclosed for providing...
Read MoreHydrogel-forming, Self-solvating Absorbable Polyester Copolymers, and Methods for Use Thereof 6,413,539 (2002)
The present invention provides novel hydrogel-forming, self-solvating, absorbable polyester copolymers capable of selective, segmental association into compliant hydrogels upon contacting an aqueous environment. Methods of using the novel polyester copolymers of the invention in humans are also disclosed for providing...
Read MoreHydrogel-Forming, Self-Solvating Absorbable Polyester Copolymers, and Methods for Use Thereof--Uses 5,714,159 (1998)
The present invention provides novel hydrogel-forming, self-solvating, absorbable polyester copolymers capable of selective, segmental association into compliant hydrogels upon contacting an aqueous environment. Methods of using the novel polyester copolymers of the invention in humans are also disclosed for providing...
Read MoreInorganic-organic melted-extruded hybrid filaments and medical applications thereof 7,465,489 (2008)
This invention deals with a family of inorganic-organic hybrid, melt-extruded filaments having variable cross-sectional geometry with a cross-sectional area ranging between 100 .mu..sup.2 and 4 mm.sup.2, wherein the inorganic...
Read MoreInorganic-Organic Melt-Extruded Hybrid Filaments and Medical Applications Thereof 7,465,489 (2008)
This invention deals with a family of inorganic-organic hybrid, melt-extruded filaments having variable cross-sectional geometry with a cross-sectional area ranging between 100μ2 and 4 mm2, wherein the inorganic component...
Read MoreInorganic-organic melt-extruded hybrid yarns and fibrous composite medical devices thereof 7,632,765 (2009)
Composite fibrous constructs are made of combinations of inorganic-organic hybrid monofilament or multifilament yarns containing at least 6 weight percent of inorganic micro-/nanoparticles and organic monofilament or multifilament yarn with typical examples of the hybrid yarn matrix made of absorbable or non-absorbable...
Read MoreInorganic-organic melt-extruded hybrid yarns and fibrous composite medical devices thereof 7,820,289 (2010)
Composite fibrous constructs are made of combinations of inorganic-organic hybrid monofilament or multifilament yarns containing at least 6 weight percent of inorganic micro-/nanoparticles and organic monofilament or multifilament yarn with typical examples of the hybrid yarn matrix made of absorb
Read MoreInterlinked solid polyethylene glycols and copolymers thereof 6,861,503 (2005)
The present invention is directed primarily to an interlinked crystalline solid polyethylene glycol composition (I-PEG) having a molecular weight of at least 20 kDa and a melting temperature of at least 40.degree. C. and its use as an absorbable device having hydrolabile ester or carbonate interlinks that allow in vivo...
Read MoreLow Fiber-Loading Composites with Hybridized Fiber/Matrix Interface 6,069,192 (2000)
Disclosed are fiber-reinforced composites having untraditionally low fiber loading and a novel form of hybridized interface. Typical examples of fiber-matrix combinations capable of developing such interfaces include surface-phosphonylated ultrahigh molecular weight polyethylene (UHMW-PE) and polypropylene (PP) yarns...
Read MoreMicromantled Drug-eluting Stent 7,416,559 (2008)
Pharmacologically active, easy-to-deploy, biomechanically compatible, inflatable, endovascular, drug-eluting stents are formed of a primary expandable polymeric or metallic construct, intimately mantled with a biomechanically compatible, polymeric microporous, microfibrous, compliant, stretchable fabric formed
Read MoreMicromantled Drug-eluting Stent 7,722,914 (2010)
Pharmacologically active, easy-to-deploy, biomechanically compatible, inflatable endovascular, drug-eluting stent are formed of a primary expandable polymeric or metallic construct, intimately mantled with a biomechanically compatible, polymeric microporous, microfibrous, compliant...
Read MoreMicroporous Polymeric Foams and Microtextured Surfaces 5,847,012 (1998)
Highly uniform microporous foam suitable for medical applications and methods for preparing these foams. The highly uniform microporous foams are of controlled pore size that may be utilized in a variety of applications. In preparing the foams, an organic crystalline polymer is melted and combined with a selected solid...
Read MoreMicroporous Polymeric Foams and Microtextured Surfaces 5,898,040 (1999)
Highly uniform microporous foam suitable for medical applications and methods for preparing these foams. The highly uniform microporous foams are of controlled pore size that may be utilized in a variety of applications. In preparing the foams, an organic crystalline polymer is melted and combined with a selected solid...
Read MoreMicroporous polymeric foams and microtextured surfaces 5,969,020 (1999)
Highly uniform microporous foam suitable for medical applications and methods for preparing these foams. The highly uniform microporous foams are of controlled pore size that may be utilized in a variety of applications. In preparing the foams, an organic crystalline polymer is melted and combined with a selected solid crystalline fugitive compound...
Read MoreModulated molecularly bonded inherently conductive polymers on substrates with conjugated multiple lamellae and shaped articles thereof 6,117,554 (2000)
Organic inherently conductive polymers, such as those based on polyaniline, polypyrrole and polythiophene, are sequentially formed in-situ onto polymeric surfaces that are chemically functionalized to molecularly bond the conductive polymers to the substrates. The polymeric substrate is preferably a preshaped or prefor...
Read MoreMolecularly bonded inherently conductive polymers on substrates and shaped articles thereof 5,849,415 (1998)
Organic inherently conductive polymers, such as those based on polyaniline, polypyrrole and polythiophene, are formed in-situ onto polymeric surfaces that are chemically activated to bond ionically the conductive polymers to the substrates. The polymeric substrate is preferably a preshaped or preformed thermoplastic film…
Read MoreMultifaceted Compositions for Post-surgical Adhesion Prevention 6,551,610 (2003)
This invention deals with an absorbable, gel-forming composition for multifaceted prevention of post-operative surgical adhesion through a plurality of physico-pharmacological modes, comprising a solution of one or more bioactive compounds in a liquid copolymeric vehicle made by end-grafting one or more cyclic monomer...
Read MorePackage components for radiochemical sterilization 7,694,813 (2010)
This invention deals with package components for radiochemical sterilization of medical or pharmaceutical products consisting of a hermetically sealed foil pack containing (1) a solid device, as in absorbable sutures and meshes, in a perforated holder or a liquid formulation in a sealed, flexible dispenser, as in absorbable cyanoacrylate-based tissue adhesive...
Read MorePackage components for radiochemical sterilization 7,694,815 (2010)
Package components for the radiochemical sterilization of medical devices contain paraformaldehyde as the precursor of the radiolytically generated, sterilizing dose of formaldehyde, premixed with a particulate solid dispersant of, preferably, polyethylene or silica gel, which facilitates the free passage...
Read MorePeracylated Insulin Compositions and Process For Making the Same 6,162,895 (2000)
A method for modifying a protein or polypeptide is disclosed which includes the steps of dispersing a protein or polypeptide in an essentially non-aqueous medium and peracylating the protein or polypeptide with a cyclic anhydride having a carbon chain substituent selected from the group consisting of alkyl and alkenyl...
Read MorePeracylated Protein-based Sutures and Fabrics and Process For Making the Same 6,254,986 (2001)
A method for modifying a protein or polypeptide is disclosed which includes the steps of dispersing a protein or polypeptide in an essentially non-aqueous medium and peracylating the protein or polypeptide with a cyclic anhydride having a carbon chain substituent selected from the group consisting of alkyl and alkenyl...
Read MorePeracylated Proteins and Synthetic Polypeptides and Process for Making the Same 5,986,050 (1999)
A method for modifying a protein or polypeptide is disclosed which includes the steps of dispersing a protein or polypeptide in an essentially non-aqueous medium and peracylating the protein or polypeptide with a cyclic anhydride having a carbon chain substituent selected from the group consisting of alkyl and alkenyl...
Read MorePhosphonylated Derivatives of Aliphatic Heterochain and Acrylate Polymers and Applications Thereof 6,395,259 (2002)
A variety of phosphonylated heterochain polymers are disclosed, including, most preferably, phosphonylated polymethyl methacrylate. For each polymeric composition the phosphorous atom of a phosphorous-containing functional group is covalently bonded to a carbon atom of the polymeric chain. The phosphorous atoms are pre...
Read MorePhosphonylated Derivatives of Aliphatic Heterochain and Acrylate Polymers and Applications Thereof 6,551,580 (2003)
A variety of phosphonylated heterochain polymers are disclosed, including, most preferably, phosphonylated polymethyl methacrylate. For each polymeric composition the phosphorous atom of a phosphorous-containing functional group is covalently bonded to a carbon atom of the polymeric chain. The phosphorous atoms are pre...
Read MorePolyester/Cyanoacrylate Tissue Adhesive Compositions 7,351,426 (2008)
This invention addresses absorbable cyanoacrylate-based tissue adhesive compositions based primarily on an alkoxy cyanoacrylate combined with one or more alkyl cyanoacrylate(s), a stabilizer...
Read MorePolyester/Cyanoacrylate Tissue Adhesive Formulations 6,299,631 (2001)
The present invention is directed to bioabsorbable adhesive/hemostatic formulations of a 2-alkoxyalkylcyanoacrylate and liquid or solid polymeric modifiers and adjuvant. The present adhesive formulations are useful as tissue adhesive/sealants, hemostatic agents, and as a means for patching or anastomic coupling of dama...
Read MorePolyester/cyanoacrylate tissue adhesive formulations 6,723,114 (2004)
The present invention is directed to bioabsorbable adhesive/hemostatic formulations of a 2-alkoxyalkylcyanoacrylate and liquid or solid polymeric modifiers and adjuvant. The present adhesive formulations are useful as tissue adhesive/sealants, hemostatic agents, and as a means for patching or anastomic coupling of dama...
Read MoreProcess of Making a Bone Healing Device 5,529,736 (1996)
The present invention is directed to polymeric bone fixation devices and processes for making the devices. In making the bone fixation devices, a polymeric material having a crystalline portion is deformed by a compressive force along a particular direction which causes molecular chains contained within the polymer to...
Read MoreRadiation and radiochemically sterilized absorbable devices with dose-controlled functional strength retention 7,709,556 (2010)
Absorbable radiation or radiochemically sterilized medical devices, including sutures, whose breaking strength and absorption profile can be modulated by controlling the total dose received during sterilization are disclosed...
Read MoreRadiochemical sterilization 5,422,068 (1995)
Radiochemical sterilization is accomplished by exposing a sterilant gas releasing substrate to an effective gas releasing amount of ionizing radiation and contacting an object to be sterilized with the released sterilant gas. Objects to be sterilized may be subjected to a combination of ionizing radiation and gas sterilant which is released by the ionizing radiation...
Read MoreSegmented Copolyesters as Compliant Absorbable Coatings and Sealants for Vascular Devices 7,348,364 (2008)
Absorbable sealants or coatings for biomedical devices which are formulated from a segmented copolyester having a molecular weight of more than...
Read MoreSelf-reinforced Ultra-high Molecular Weight Polyethylene Composite Medical Implants 5,834,113 (1998)
The invention provides composites of ultra-high molecular weight polyethylene reinforced with ultra-high molecular weight polyethylene anisotropic reinforcement of high strength and modulus. The composites have superior mechanical properties relative to non-filled ultra-high molecular weight polyethylene, including hig...
Read MoreSelf-reinforced Ultra-high Molecular Weight Polyethylene Composites 5,824,411 (1998)
The invention provides composites of ultra-high molecular weight polyethylene reinforced with ultra-high molecular weight polyethylene anisotropic reinforcement of high strength and modulus. The composites have superior mechanical properties relative to non-filled ultra-high molecular weight polyethylene, including hig...
Read MoreStabilized Polyester/Cyanoacrylate Tissue Adhesive Formulation 7,083,634 (2006)
The present invention is directed to adhesive/hemostatic formulations of 2-alkoxyalkyl cyanoacrylate, an absorbable liquid or solid polymeric modifier, and a general stabilizer against premature anionic polymerization of cyanoacrylates. The present formulations are useful as tissue adhesives/sealants...
Read MoreSurface Electroconductive Biostable Polymeric Articles 7,381,664 (2008)
Organic inherently conductive polymers, such as those based on polyaniline, polypyrrole and polythiophene, are formed in situ onto polymeric surfaces that are chemically activated to bond, ionically, the conductive polymers to the substrates...
Read MoreSurface modified glasses and composites thereof 5,874,509 (1999)
An inorganic glass having an aliphatic polymer covalently bonded to the surface thereof is disclosed for providing improved adhesion to a matrix polymer when the glass is employed as a composite filler, as well as for the formation of a composite absent a separate matrix...
Read MoreTissue Protecting Spray-on Copolymeric Film Composition 7,842,749 (2010)
This invention deals with a tissue protecting, spray-on film composition comprising an amphiphilic film-forming, segmented/block copolymer derived form at least one water-soluble monomer and at least another water-insoluble monomer, wherein the film can be formed from a water soluble organic solvent...
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Vascular Graft European Patent EP 1 582 547 (2005)
A vascular graft comprising a sealant made of an absorbable crystalline monocentric polyaxial copolyester comprising a central nitrogen atom with chains extending outwardly therefrom. Each chain consists of an inner amorphous component and an outer crystalline component. Each of the components is derived from at least one cyclic monomer selected from the group consisting of glycolide, l-lactide, Ɛ-caprolactone, and trimethylene carbonate...
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